Ho Chi Minh City, the largest metropolis in Vietnam, is also facing a series of cultural challenges in the context of globalization and rapid urbanization. Increased migration, economic pressures, consumer lifestyles, and digital technology have eroded community spirit and changed urban values. At the same time, the local cultural identity is at risk of fading when public spaces are commercialized and the living environment is degraded. From the perspective of cultural philosophy and development philosophy, the study emphasizes the need for harmony between economy, spirit, and environment, thereby affirming the role of the humanistic value system and Vietnamese identity in creating a Ho Chi Minh City with modernity, creativity, and sustainability.