This two-season field experiment investigated the impact of spacing and variety on maize (Zea mays L.) growth and yield in Makurdi, Nigeria. Two maize varieties (Sammaz 51 and Sammaz 14) were evaluated at three spacing regimes (15, 20, and 25 cm). A randomized complete block design with three replications was employed. Physiological and yield-related traits were assessed, including, plant height, the number of leaves, stem diameter, and adventitious roots per plant, were measured. Other characters like stem girth, Adventurous root, Cob length, Cob diameter, Number of line per cob, Number of cob/plant, number of seed per cob, Shelling (%), 1000 seed weight and Yield (t/ha) were also recorded. The results of the investigation revealed that maize generally responded to both spacing and variety. All the parameters studies have significantly (P ≤ 0.05) responded to varietal effects, the use of Sammaz 14 was observed to perform higher in both growth character such plant height(123.30), the number of leaves (16.27), stem girth (5.98), adventitious roots per plant (6.10), Cob length (14.67), Cob diameter (9.22), Number of line per cob (15.30), Number of cob per plant (2.74), number of seed per cob (620.43), Shelling (80.92 %), 1000 seed weight(952.43g) and Yield (5.42t/ha) Maize grown in spacing 15cm outgrows those cultivated in spacing 20 and 25cm in both vegetative and reproductive character such as plant height (137.54), the number of leaves (16.24), stem girth (5.00), Adventurous root (6.01), Cob length (15.21), Cob diameter (9.73), Number of line per cob (16.54), Number of cob per plant (2.90), number of seed per cob (621.32), Shelling (85%), 1000 seed weight (901.65g) and Yield (5.54t/ha). On seasonal effect the cultivation of maize in 2024 remained superior in all the parameters under consideration. Optimal maize production in Makurdi can be achieved using 15 cm spacing and Sammaz 14. Based on the results obtained it can be suggested that famers in the location can use spacing 15cm and Sammaz 14 boast maize production for optimum yield.