Major depressive disorder is an important mental health problem that can seriously affect individuals' quality of life and lead to deep changes in various fields. From a clinical point of view, this disorder causes significant and sustainable changes in the general mood, as well as energy level, sleep level, appetite and general functionality. The effects of this disorder in society leave deep and lasting traces not only on the lives of individuals, but also on social structures and social relations. In particular, individuals diagnosed with depression may experience significant difficulties in their social interactions due to a number of psychological disorders, which leads to their loneliness and more complex social problems. Depression can adversely affect families and friends because it makes the management of individuals in a negative way, which can cause greater problems by potentially weakening social support systems. Therefore, the fight against this disorder is critical not only for the health of individuals, but also for the health of the society.