Kalanchoe marnieriana (Crassulaceae), commonly known as succulent’s flowery plant, is regarded as extremely useful in traditional medicine. Because of its analgesic and anti-inflammatory qualities, this succulent is frequently used to treat a variety of illnesses. Kalanchoe is also used by many because of its ability to promote wound healing and strengthen the immune system in general. Its stems, leaves, and flowers are used to treat a variety of illnesses. This study aims to determine the quality standardization, evaluation of the phytochemical and anthelmintic activities on earthworms using an extract of Kalanchoe marnieriana.  Determining the flavonoid concentration of Kalanchoe marnieriana extracts is the key objective of standardization. The result can often be achieved by using rutin as a reference chemical using the AlCl3 technique to measure absorbance in a spectrophotometer with ultraviolet-visible wavelengths. The results are then expressed in the substance equivalents.  Phytochemical evaluation was done by some standard tests.  In vitro anthelmintic activity was assessed by the earthworm method. The phytochemical test revealed that microgreens extract of K. Marnieriana contains alkaloids, reducing sugar, glycosides, terpenoids, saponins, carbohydrates, and protein. Results & Discussion: The accurate validation and description of a phytotherapeutic product's or herbal preparation's properties, such as extracts and crude pharmaceuticals, is crucial to its quality. The creation of uniform goods is the final outcome of this procedure, improving their medium- and long-term safety and effectiveness. The plant material and extract were thus characterised, offering crucial details regarding their physicochemical characteristics as well as scientific backing for possible therapeutic uses of the extract or an isolated compound. Conclusion: Ethnomedicine has long used species of the genus Kalanchoe for therapeutic purposes because of its exceptional healing qualities. When employed in traditional medicine, the chemical and physical similarities between several species can cause confusion. The purpose of this review is to give a summary and discussion of the kalanchoe species' documented traditional usage, botanical characteristics, chemical components, and pharmacological potential.